Why Avoid B6?


Choosing a B complex supplement without B6 can be a wise decision, especially considering toxicity risks and individual supplementation needs. Here’s why you might want to avoid B6 in your food supplement:

1. Risk of B6 Toxicity

Unlike other water-soluble B vitamins, B6 can accumulate in the body, leading to nerve damage (neuropathy) if taken in excess.

Symptoms include:

  • Numbness and tingling in hands and feet
  • Burning pain or loss of coordination
  • Difficulty walking or clumsiness

Long-term intake of 50 mg+ daily can cause symptoms in some people.

2. B6 is Usually Not Deficient

We generally get enough B6 from food (poultry, fish, bananas, potatoes, etc.), making supplementation unnecessary.

  • Unlike B12 or folate, which are crucial for preventing anaemia and neurological issues, extra B6 doesn’t provide additional benefits unless there’s a true deficiency.
  • B6 deficiency is rare, occurring mostly in cases of alcoholism, kidney disease, or medication-induced depletion.

3. Individual Supplementation is Better

If you need B6, taking it separately in a controlled dose is better than using a B-complex, which may contain excessive amounts.

  • Allows flexibility to adjust intake based on individual needs.
  • Some B-complex supplements far exceed daily requirements (often 50-100 mg or more), increasing the risk of toxicity.

4. No Clear Benefit of High-Dose B6 in a B-Complex

Some assume that "more is better," but that’s not the case with B6.

  • High doses don’t boost energy like B12.
  • While B6 supports neurotransmitter production, excess amounts don’t enhance cognitive function or mood in healthy individuals.
  • Unlike other B vitamins, B6 isn’t rapidly excreted and can accumulate over time.

5. A Safer, Targeted B-Complex Formula Exists

FETTYL B Complex without B6 is designed for:

  • People at risk of B6 toxicity (e.g., those with neuropathy or long-term supplementation).
  • Those who get enough B6 from diet but need other B vitamins: B12, folate, B1, B2, B3, B5, and B7.
  • Individuals with MTHFR mutations who need methylfolate and methylcobalamin without unnecessary B6.

B complex without B6 is a safer choice if:

  •  You are concerned about B6 toxicity or neuropathy
  •  You already get enough B6 from food
  •  You prefer to take B6 separately if needed
  •  You want to avoid excessive or unnecessary supplementation.

Understanding B6 Toxicity